The Hogben test, developed somewhat accidentally by the British zoologist Lancelot Hogben, consisted of injecting a womans urine under the skin of a female frog and then checking to see whether or not, hours later, the creature produced a cluster of eggs. Caractristiques. It would then be placed in a tank of water. 1 African clawed frogs used to be the best human pregnancy tests in the world. 2 Doctors would inject a woman's urine into the back of a female frog; if positive, the frog would lay eggs. 3 Frog or "Hogben" tests were commonplace from the 1940s through the early 1960s. More items By the 1940s in Britain, there were three specialized centers covered by the National Health Service (NHS) where doctors would send urine samples to get tested. Flashcards. It employed the African clawed frog and produced findings without the need to cut the animal open. Six to twelve hours later, the frog would produce a cluster of black and white spheres.
There is a greater risk to a pregnant woman and her baby if TB disease is not diagnosed and treated. If a chlamydia test result has not been documented, the partner may be treated with a single dose of oral cefixime 800 mg plus oral doxycycline 100 mg 2 times/day for 7 days. American Journal of Obstetrics and Gynecology, 01 May 1946, 51: 672-677 DOI: 10.1016/s0002-9378(15)30124-1 PMID: 21025151 .
clarisseanntolang.
The Hogben test, named after the British zoologist Lancelot Hogben, was one of the most reliable and rapid pregnancy tests from the 1940s to the 1960s. Shortly thereafter, British zoologist Lancelot Hogben pioneered the frog pregnancy test while conducting research at the University of Cape Town in South Africa. The frog pregnancy test, named the Hogben Test quickly became popular. History of the Hogben test Br Med J. Women could not send their samples directly; in fact, if they tried to, they would not be tested. This type of pregnancy test can only be done at a doctor's office. Obstet Gynecol 2002;100:8017. You are going to email the following Aschheim-Zondek and Hogben Pregnancy Tests Modified and Compared. If the woman was pregnant, then within 5-12 hours, the female frog would lay eggs. If the woman was pregnant, then within 5-12 hours, the female frog would lay eggs.
Bonhams. The South African clawed toad Xen@tls Laevis was first introduced as an assay animal by Hogben in 1930 and is now well established that they can be used as a reliable test animal for pregnancy diagnosis in humans, and assay of melanophore-expanding hormone. History of the Hogben test.
In a series of tests with Prepuerin done in parallel with the Hogben test the former has shown a higher sensitivity. 1949 Jul 2;2(4617):17. doi: 10.1136/bmj.2.4617.17. In South Africa, Lancelot Hogben adapted the A-Z Test for frogs, inventing the Hogben Test. Meanwhile, Dr. Maurice Friedman made his breakthrough with rabbits. Injecting urine into female rabbits produces much the same results as the A-Z Test. If hCG is present, the urine stimulates changes to the rabbit's ovaries within just a few days. Author links open overlay panel E.C. The best time to take a pregnancy test is after your period is late. Hogben M, St Lawrence JS, Kasprzyk D, et al. Spell. It takes longer than a urine test to get results, but it can detect a pregnancy earlier than a urine test (about 10 days after conception, compared to typically 2 weeks or more for a urine test). Hogben Test. What is hCG? The Hogben test, is a subsequent alternative to the rabbit test. There have been three false positive results with The test is inexpensive, low technology and is point of care, however, it is insensitive, particularly in men. An evaluation of the Hogben pregnancy test. The result was quite unsatisfactory.2. PMID: 21001524 DOI: 10.1136/bmj.2.4475.554 No abstract available. ROI for Hogben. Match. Write. Learn. - Liz Curtis Higgs, The Women of Christmas: Experience the Season Afresh with Elizabeth Numerous reviews have addressed the effects of caffeine on either physical or cognitive performance alone (Burke, 2008, Davis and Green, 2009, Graham, 2001, Lieberman et al., 2010, Shearer and Graham, 2014, Spriet, 2014).However, since Weiss and Laties did so in 1962 there have been only a few attempts to summarize caffeines effects on both physical and WTF Fun Facts. To assist in prenatal tests, such as an amniocentesis. Your Personal Message . If the woman was pregnant, the frog would ovulate in a matter of hours. STUDY. Several routine lab tests are done early in pregnancy, including.
The urine samples were injected into African clawed frogs. Elizabeth's words to Mary, then, were a confirmation of God's promise and more powerful than any blood test." Terms in this set (18) Test animal for aschheim-zondek. Intramuscular (gastrocnemius) ROI for Frank-Berman. Source: How a Frog Became the First Mainstream Pregnancy Test The Atlantic
hCG is a hormone produced by your placenta when you are pregnant. 6.
Sixty-five studies (denoted by * in the reference list) out of 216 initial citations were included in the meta-analysis (Chart 1).The studies enrolled 1408 participants (931 males, 455 females, 22 with undisclosed gender), with a mean age of 36.1 15.1 years, BMI of 25.9 2.6 kg/m 2 and VO 2 max of 33.1 10.2 mL x min-1 x kg-1.Of these participants, 466 engaged in 1946 Oct 12;2:554. doi: 10.1136/bmj.2.4475.554. This type of pregnancy test can be done at home or at a doctor's office. Also, pregnant women typically are tested for specific diseases and infections early in pregnancy, including. TB skin testing is considered both valid and safe throughout pregnancy. 1 Invented by Selmar Aschheim and Bernhard Zondek in Berlin in the late 1920s (Brer, 2004; Finkelstein & Zondek, 1966; Hinz, Ebert, & Goetze, 1994; Rudloff & Ludwig, 2005; Schneck, 1997), by the mid 1930s a diagnostic service in Edinburgh was performing thousands of tests every Throughout the 1930s, 40s, 50s, this was the primary pregnancy test available to women. Results. Aschheim-Zondek and Hogben pregnancy tests modified and compared Br Med J. The Hogben test was both rapid and reliable, and it spread quickly throughout Europe and the United States over the next two decades. Gravity. History of the Hogben test. The pharmacist would inject a mature female frog with an early morning urine sample from the woman who suspected she might be pregnant. ROI for Kupperman. Sexually transmitted disease screening by United States obstetricians and gynecologists. Four hundred tests for pregnancy were undertaken using native urine in performing the Hogben test. Ascheim and Zondek (1928) based their test on the discovery that pregnancy urine contains a substance which is gonadotrophic when injected intomice. Aschheim-Zondek and Hogben pregnancy tests modified and compared. In this way, Hogben serendipitously discovered a human pregnancy test. He knew that the ox extract chemically resembled human chorionic gonadotropin (HCG), a hormone released by pregnant women. He confirmed that female Xenopus frogs, when injected with urine from a pregnant woman, ovulated within hours.
The test, which was known as the Hogben test, involved collecting fresh urine and injecting it under the skin of a female frog. Haemagglutination inhibition tests are easy to perform and easy to read. FOOTE EC, JONES GE. The Hogben test uses female frogs, unlike the Xenopus (/ z n p s /) (Gk., , xenos=strange, , pous=foot, commonly known as the clawed frog) is a genus of highly aquatic frogs native to sub-Saharan Africa.Twenty species are currently described within it.
Starting in 1960, antibodies allowed testing for pregnancy to be done in doctors offices, making pregnancy testing faster and more routine.
pisa test - sample papers brilliant questions ; children of the forest - jenukurba ; beauty of corruption - s. visvanathan must read ; reinventing gandhi - s. visvanathan great essay on gandhi ; prof. c. v. seshadhri - shiv visvanathan india's great people's scientist ; science, hegemony and violence - ed. Learning and Teaching German. It appears shortly after the embryo attaches to the wall of the uterus. The Hogben test. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Seegar Jones M.D.. Show more Hogbentest in pregnancy J. SHEAANDA. Article Metrics. Though not the first laboratory pregnancy test, it was the first to be used on a large scale. Pregnancy was confirmed if the frog spawned within 18 hours. ashis nandy Recommended articles cannot be displayed at this time.
Everyone's fertile window (the time when they can get pregnant) is different, depending on when they ovulate. As early as the 1940s, frogs were being used in pharmacies as 'pregnancy tests'. MTZ is a class B drug and several meta-analyses have found it to be safe in pregnant women in all stages of pregnancy [72, 73]. An Evaluation of the Hogben Pregnancy Test. TNZ has not been evaluated in pregnant women and remains a class C drug. Modern pregnancy tests continue to operate on the basis of testing for the presence of the hormone hCG in the blood or urine, but no longer require the use of a live animal. In the 1940s, one of the first female pregnancy tests (the Hogben test) involved injecting a womans urine into a female frogs skin. The results are reproducible and are not subject to the vagaries ofsupply and temperament inherent in tests using living creatures. A prototype of the Predictor pregnancy test (left) and the test as it went to market in the late 1970s (right). Il est possible de se procurer en pharmacie, en grande surface ou sur des sites internet ddis [1], un test qui dtecte le taux de hCG (l'hormone chorio-gonadotrophique humaine) contenue dans l'urine.Le test ne fonctionne correctement que deux Authors F W LANDGREBE, B M HOBSON. In the 1940s, one of the first female pregnancy tests (the Hogben test) involved injecting a womans urine into a female frogs skin. The Hogben Test involved injecting the womans urine into the African clawed frog.
Foote M.A. urinalysis.
CAPTCHA . To examine the fetal anatomy for abnormalities. Teachers and students can use these comprehensive German language guides to improve reading, writing, and comprehension skills for beginner, intermediate, and advanced levels. Summary1. hepatitis B and hepatitis C. rubella. Prior to that, it involved injecting their urine into mice or rabbits, which were then dissected to see if the animals ovaries had enlarged. hogben pregnancy test meaning in Hindi with examples: click for more detailed meaning of hogben pregnancy test in Hindi with examples, definition, pronunciation and example sentences. Un test de grossesse permet de savoir si une femme est enceinte ou non. View article metrics Symptoms in the beginning stages of HIV may be hard to spot. TB blood tests also are safe to use during pregnancy, but have not been evaluated for diagnosing TB infection in pregnant women. The results are reproducible and are not subject to the vagaries of supply and temperament inherent in tests using living creatures. J. N. WARRACK FromthePregnancy Diagnosis Unit, City GeneralHospital, Sheffield sYNoPsis Haemagglutination inhibition tests are easy to perform and easy to read. References Il est ralisable de diffrentes faons. In a series of tests with Prepuerin done in parallel with the Hogben test the former has shown a higher sensitivity. The Hogben test, as it came to be known throughout the 1940s, 50s and 60s, involved injecting a sample of urine under the skin of a South African clawed frog.
An African clawed frog, or Xenopus laevis. African clawed frogs used to be the best human pregnancy tests in the world. Doctors would inject a woman's urine into the back of a female frog; if positive, the frog would lay eggs. G.E. All pregnant people should be screened for hepatitis C during each pregnancy, except in settings where the prevalence of HCV infection (HCV RNA-positivity) is <0.1%. The two best-known species of this genus are Xenopus laevis and Xenopus tropicalis, which are commonly studied as model organisms for developmental
If the answer was yes, congratulations were in order. Author L HOGBEN. Pregnancy Test Bioassays. Topics. Testing During Pregnancy. Pregnancy Diagnosis Laboratory, Department of Obstetrics and Gynaecology, University of Edinburgh Search for more papers by this author W. A. Barr B.Sc., Ph.D. , There have been three false positive results with Prepuerin tests in the series but it was not established on general grounds that pregnancy was not in fact present. Obstetrics and WTF Fun Facts. Test. In an act of hormonal trickery, hCG basically fools the rabbit's body into temporarily thinking it's pregnant. A later alternative to the rabbit test, known as the "Hogben test," used the African clawed frog, and yielded results without the need to cut the animal open. urine culture. 6. Created by. complete blood count (CBC) blood type and Rh factor. Subcatenous (dorsal lymph sac) ROI for Galli-Mainini. If you dont want to wait until youve missed your period, at least wait for one to two weeks after you had sex to take a test.
Source: How a Frog Became the First Mainstream Pregnancy Test The Atlantic. Midtrimester (also called the 18- to 20-week scan) To confirm the due date (a due date set in the first trimester is rarely changed) To determine the number of fetuses and examine the placental structures. Modern pregnancy tests still look for the hormone hCG in the blood or urine.
[iii] Hepatitis C testing is usually initiated with an HCV antibody test which, if positive, indicates a Injecting urine into female rabbits produces much the same results as the A-Z Test.
PLAY. Blood test. Symptoms of acute infection may begin around 2 to 4 weeks after first exposure to the virus.
"Except for some queasiness in the morning or tiredness in the afternoon, Mary may not have noticed any real signs of her pregnancy yet. If hCG is present, the urine stimulates changes to the rabbit's ovaries within just a few days. Answer (1 of 11): Mainly by checking womans urine, and by observing if there were usual symptoms of pregnancy. By 1971, an at-home version of this antibody-based test was available in Canada, although at-home testing didnt reach the USA until 1977. The Hogben test for pregnancy was quite unsatisfactory and very considerable variation was experienced in the sensitivity of the individual toad to injection of the chorionic gonadotrophin. June 2, 2015. Subcutaneous.
There is a greater risk to a pregnant woman and her baby if TB disease is not diagnosed and treated. If a chlamydia test result has not been documented, the partner may be treated with a single dose of oral cefixime 800 mg plus oral doxycycline 100 mg 2 times/day for 7 days. American Journal of Obstetrics and Gynecology, 01 May 1946, 51: 672-677 DOI: 10.1016/s0002-9378(15)30124-1 PMID: 21025151 .
clarisseanntolang.
The Hogben test, named after the British zoologist Lancelot Hogben, was one of the most reliable and rapid pregnancy tests from the 1940s to the 1960s. Shortly thereafter, British zoologist Lancelot Hogben pioneered the frog pregnancy test while conducting research at the University of Cape Town in South Africa. The frog pregnancy test, named the Hogben Test quickly became popular. History of the Hogben test Br Med J. Women could not send their samples directly; in fact, if they tried to, they would not be tested. This type of pregnancy test can only be done at a doctor's office. Obstet Gynecol 2002;100:8017. You are going to email the following Aschheim-Zondek and Hogben Pregnancy Tests Modified and Compared. If the woman was pregnant, then within 5-12 hours, the female frog would lay eggs. If the woman was pregnant, then within 5-12 hours, the female frog would lay eggs.
Bonhams. The South African clawed toad Xen@tls Laevis was first introduced as an assay animal by Hogben in 1930 and is now well established that they can be used as a reliable test animal for pregnancy diagnosis in humans, and assay of melanophore-expanding hormone. History of the Hogben test.
In a series of tests with Prepuerin done in parallel with the Hogben test the former has shown a higher sensitivity. 1949 Jul 2;2(4617):17. doi: 10.1136/bmj.2.4617.17. In South Africa, Lancelot Hogben adapted the A-Z Test for frogs, inventing the Hogben Test. Meanwhile, Dr. Maurice Friedman made his breakthrough with rabbits. Injecting urine into female rabbits produces much the same results as the A-Z Test. If hCG is present, the urine stimulates changes to the rabbit's ovaries within just a few days. Author links open overlay panel E.C. The best time to take a pregnancy test is after your period is late. Hogben M, St Lawrence JS, Kasprzyk D, et al. Spell. It takes longer than a urine test to get results, but it can detect a pregnancy earlier than a urine test (about 10 days after conception, compared to typically 2 weeks or more for a urine test). Hogben Test. What is hCG? The Hogben test, is a subsequent alternative to the rabbit test. There have been three false positive results with The test is inexpensive, low technology and is point of care, however, it is insensitive, particularly in men. An evaluation of the Hogben pregnancy test. The result was quite unsatisfactory.2. PMID: 21001524 DOI: 10.1136/bmj.2.4475.554 No abstract available. ROI for Hogben. Match. Write. Learn. - Liz Curtis Higgs, The Women of Christmas: Experience the Season Afresh with Elizabeth Numerous reviews have addressed the effects of caffeine on either physical or cognitive performance alone (Burke, 2008, Davis and Green, 2009, Graham, 2001, Lieberman et al., 2010, Shearer and Graham, 2014, Spriet, 2014).However, since Weiss and Laties did so in 1962 there have been only a few attempts to summarize caffeines effects on both physical and WTF Fun Facts. To assist in prenatal tests, such as an amniocentesis. Your Personal Message . If the woman was pregnant, the frog would ovulate in a matter of hours. STUDY. Several routine lab tests are done early in pregnancy, including.
The urine samples were injected into African clawed frogs. Elizabeth's words to Mary, then, were a confirmation of God's promise and more powerful than any blood test." Terms in this set (18) Test animal for aschheim-zondek. Intramuscular (gastrocnemius) ROI for Frank-Berman. Source: How a Frog Became the First Mainstream Pregnancy Test The Atlantic
hCG is a hormone produced by your placenta when you are pregnant. 6.
Sixty-five studies (denoted by * in the reference list) out of 216 initial citations were included in the meta-analysis (Chart 1).The studies enrolled 1408 participants (931 males, 455 females, 22 with undisclosed gender), with a mean age of 36.1 15.1 years, BMI of 25.9 2.6 kg/m 2 and VO 2 max of 33.1 10.2 mL x min-1 x kg-1.Of these participants, 466 engaged in 1946 Oct 12;2:554. doi: 10.1136/bmj.2.4475.554. This type of pregnancy test can be done at home or at a doctor's office. Also, pregnant women typically are tested for specific diseases and infections early in pregnancy, including. TB skin testing is considered both valid and safe throughout pregnancy. 1 Invented by Selmar Aschheim and Bernhard Zondek in Berlin in the late 1920s (Brer, 2004; Finkelstein & Zondek, 1966; Hinz, Ebert, & Goetze, 1994; Rudloff & Ludwig, 2005; Schneck, 1997), by the mid 1930s a diagnostic service in Edinburgh was performing thousands of tests every Throughout the 1930s, 40s, 50s, this was the primary pregnancy test available to women. Results. Aschheim-Zondek and Hogben pregnancy tests modified and compared Br Med J. The Hogben test was both rapid and reliable, and it spread quickly throughout Europe and the United States over the next two decades. Gravity. History of the Hogben test. The pharmacist would inject a mature female frog with an early morning urine sample from the woman who suspected she might be pregnant. ROI for Kupperman. Sexually transmitted disease screening by United States obstetricians and gynecologists. Four hundred tests for pregnancy were undertaken using native urine in performing the Hogben test. Ascheim and Zondek (1928) based their test on the discovery that pregnancy urine contains a substance which is gonadotrophic when injected intomice. Aschheim-Zondek and Hogben pregnancy tests modified and compared. In this way, Hogben serendipitously discovered a human pregnancy test. He knew that the ox extract chemically resembled human chorionic gonadotropin (HCG), a hormone released by pregnant women. He confirmed that female Xenopus frogs, when injected with urine from a pregnant woman, ovulated within hours.
The test, which was known as the Hogben test, involved collecting fresh urine and injecting it under the skin of a female frog. Haemagglutination inhibition tests are easy to perform and easy to read. FOOTE EC, JONES GE. The Hogben test uses female frogs, unlike the Xenopus (/ z n p s /) (Gk., , xenos=strange, , pous=foot, commonly known as the clawed frog) is a genus of highly aquatic frogs native to sub-Saharan Africa.Twenty species are currently described within it.
Starting in 1960, antibodies allowed testing for pregnancy to be done in doctors offices, making pregnancy testing faster and more routine.
pisa test - sample papers brilliant questions ; children of the forest - jenukurba ; beauty of corruption - s. visvanathan must read ; reinventing gandhi - s. visvanathan great essay on gandhi ; prof. c. v. seshadhri - shiv visvanathan india's great people's scientist ; science, hegemony and violence - ed. Learning and Teaching German. It appears shortly after the embryo attaches to the wall of the uterus. The Hogben test. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Seegar Jones M.D.. Show more Hogbentest in pregnancy J. SHEAANDA. Article Metrics. Though not the first laboratory pregnancy test, it was the first to be used on a large scale. Pregnancy was confirmed if the frog spawned within 18 hours. ashis nandy Recommended articles cannot be displayed at this time.
Everyone's fertile window (the time when they can get pregnant) is different, depending on when they ovulate. As early as the 1940s, frogs were being used in pharmacies as 'pregnancy tests'. MTZ is a class B drug and several meta-analyses have found it to be safe in pregnant women in all stages of pregnancy [72, 73]. An Evaluation of the Hogben Pregnancy Test. TNZ has not been evaluated in pregnant women and remains a class C drug. Modern pregnancy tests continue to operate on the basis of testing for the presence of the hormone hCG in the blood or urine, but no longer require the use of a live animal. In the 1940s, one of the first female pregnancy tests (the Hogben test) involved injecting a womans urine into a female frogs skin. The results are reproducible and are not subject to the vagaries ofsupply and temperament inherent in tests using living creatures. A prototype of the Predictor pregnancy test (left) and the test as it went to market in the late 1970s (right). Il est possible de se procurer en pharmacie, en grande surface ou sur des sites internet ddis [1], un test qui dtecte le taux de hCG (l'hormone chorio-gonadotrophique humaine) contenue dans l'urine.Le test ne fonctionne correctement que deux Authors F W LANDGREBE, B M HOBSON. In the 1940s, one of the first female pregnancy tests (the Hogben test) involved injecting a womans urine into a female frogs skin. The Hogben Test involved injecting the womans urine into the African clawed frog.
Foote M.A. urinalysis.
CAPTCHA . To examine the fetal anatomy for abnormalities. Teachers and students can use these comprehensive German language guides to improve reading, writing, and comprehension skills for beginner, intermediate, and advanced levels. Summary1. hepatitis B and hepatitis C. rubella. Prior to that, it involved injecting their urine into mice or rabbits, which were then dissected to see if the animals ovaries had enlarged. hogben pregnancy test meaning in Hindi with examples: click for more detailed meaning of hogben pregnancy test in Hindi with examples, definition, pronunciation and example sentences. Un test de grossesse permet de savoir si une femme est enceinte ou non. View article metrics Symptoms in the beginning stages of HIV may be hard to spot. TB blood tests also are safe to use during pregnancy, but have not been evaluated for diagnosing TB infection in pregnant women. The results are reproducible and are not subject to the vagaries of supply and temperament inherent in tests using living creatures. J. N. WARRACK FromthePregnancy Diagnosis Unit, City GeneralHospital, Sheffield sYNoPsis Haemagglutination inhibition tests are easy to perform and easy to read. References Il est ralisable de diffrentes faons. In a series of tests with Prepuerin done in parallel with the Hogben test the former has shown a higher sensitivity. The Hogben test, as it came to be known throughout the 1940s, 50s and 60s, involved injecting a sample of urine under the skin of a South African clawed frog.
An African clawed frog, or Xenopus laevis. African clawed frogs used to be the best human pregnancy tests in the world. Doctors would inject a woman's urine into the back of a female frog; if positive, the frog would lay eggs. G.E. All pregnant people should be screened for hepatitis C during each pregnancy, except in settings where the prevalence of HCV infection (HCV RNA-positivity) is <0.1%. The two best-known species of this genus are Xenopus laevis and Xenopus tropicalis, which are commonly studied as model organisms for developmental
If the answer was yes, congratulations were in order. Author L HOGBEN. Pregnancy Test Bioassays. Topics. Testing During Pregnancy. Pregnancy Diagnosis Laboratory, Department of Obstetrics and Gynaecology, University of Edinburgh Search for more papers by this author W. A. Barr B.Sc., Ph.D. , There have been three false positive results with Prepuerin tests in the series but it was not established on general grounds that pregnancy was not in fact present. Obstetrics and WTF Fun Facts. Test. In an act of hormonal trickery, hCG basically fools the rabbit's body into temporarily thinking it's pregnant. A later alternative to the rabbit test, known as the "Hogben test," used the African clawed frog, and yielded results without the need to cut the animal open. urine culture. 6. Created by. complete blood count (CBC) blood type and Rh factor. Subcatenous (dorsal lymph sac) ROI for Galli-Mainini. If you dont want to wait until youve missed your period, at least wait for one to two weeks after you had sex to take a test.
Source: How a Frog Became the First Mainstream Pregnancy Test The Atlantic. Midtrimester (also called the 18- to 20-week scan) To confirm the due date (a due date set in the first trimester is rarely changed) To determine the number of fetuses and examine the placental structures. Modern pregnancy tests still look for the hormone hCG in the blood or urine.
[iii] Hepatitis C testing is usually initiated with an HCV antibody test which, if positive, indicates a Injecting urine into female rabbits produces much the same results as the A-Z Test.
PLAY. Blood test. Symptoms of acute infection may begin around 2 to 4 weeks after first exposure to the virus.
"Except for some queasiness in the morning or tiredness in the afternoon, Mary may not have noticed any real signs of her pregnancy yet. If hCG is present, the urine stimulates changes to the rabbit's ovaries within just a few days. Answer (1 of 11): Mainly by checking womans urine, and by observing if there were usual symptoms of pregnancy. By 1971, an at-home version of this antibody-based test was available in Canada, although at-home testing didnt reach the USA until 1977. The Hogben test for pregnancy was quite unsatisfactory and very considerable variation was experienced in the sensitivity of the individual toad to injection of the chorionic gonadotrophin. June 2, 2015. Subcutaneous.